- 1). Spray the weeds with a non-selective post-emergent herbicide like Round-Up, Ortho or Spectracide. Follow the manufacturer's instructions. Coat the weed's foliage thoroughly, but before the point of runoff. Take care not to spray neighboring grass or other desirable plants. Non-selective herbicides will kill any plants that they come into contact with.
- 2). Wait for the weeds to die. It may take 72 hours or more for the weeds to yellow, wither and fade.
- 3). Dig the dead weeds out of the cracks in the brick with a pavement weeder.
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