Mild Reactions

• Some who have used he shou wu reported mild gastrointestinal distress, including diarrhea and nausea. Most of the reports of these side effects come from those who ingested the unprocessed herb.
  
  

Major Reactions

• In rare cases, some people have reported liver-related side effects. A few people experienced hepatitis or jaundice after taking he shou wu. Also, taking too much he shou wu, there is a possibility of numbness in the hands and feet.
  
  

Source

• Not all sources of he shou wu are reputable. Some distributors use potentially toxic ingredients to process the he shou wu. The ingredients can cause any number of side effects. For this reason, you should use caution when buying herbal supplements.