Ketoconazole is an antifungal in that it works to prevent the growth of fungi.
It is used to treat fungi infections especially those on the skin and nails.
It is especially used for people who have a compromised immune system such as HIV patients and patients undertaking chemotherapy treatment.
The antifungal drug is sold under the brand names such as Nizoral shampoo from Johnson and Johnson, USA and Sebizole from Douglas Pharmaceuticals, Australia.
The medication is sold in different forms including tablets, topical cream or anti dandruff shampoo.
History The Ketoconazole medication was discovered by lab scientists in the United States in 1976.
However, the drug underwent various clinical tests and further laboratory examinations before it got the approval to be used as medication to be sold commercially.
It was formally released for use and commercial distribution in 1981 with the approval of FDA and the approval followed that of Griseofulvin as being an oral treatment for infections caused by fungi attacks.
Mechanism of Action Ketoconazole works to inhibit the synthesis of fungi that yields the fungi cell membrane and fungi enzymes that lead to fungi growth.
It is used in many other medications and substances such as steroids and in precursors of testosterone due to this synthesis inhibition.
Ketoconazole and Hair Loss Some experiments of the Nizoral shampoo have resulted in s significant treatment of men hair loss.
Experiments conducted in 1998 revealed that a shampoo with a 2% concentration of Ketoconazole could significantly increase the density of hair for the person experiencing hair loss.
However, the experiments were not exhaustive and other experiments have been conducted since then, These experiments reveal that the Nizoral shampoo has a hair growth stimulant that can be used to significantly reverse the effects of hair loss.
Resistance to the Antifungal Not all fungi get inhibited by the Nizoral shampoo or other types of Ketoconazole medication.
Some types of fungi have been observed to be resistant to this medication and will therefore not treat the diseases caused by the fungi.
Especially in cases of HIV, the drug has been noted as being successfully resisted by various yeast infections such as Candida albicans.
This resistance has been explained as being a mutation of the fungi during the synthesis process.
Therefore, if the specific fungi infection does not go away with the treatment, you should seek medical advice and have your doctor get you a replacement drug for your infection.
Side Effects of the Medication The Nizoral shampoo has mild side effects on a few of the patients including dryness of the skin and also oiliness or excessive dryness of the hair and the scalp.
For the other types of mediation, there are possible itchiness and skin rash especially with the cream and other side effects including excessive irritation or sting like effects which commence with the use of the medication.
If you have concerns with the side effects, you should discuss this with your doctor.
You should also alert the doctor in case such side effects arise so as to have them recommend a solution for the side effects.
However, by and large, these side effects are very rare and occur only to about 1% of the users.
It is used to treat fungi infections especially those on the skin and nails.
It is especially used for people who have a compromised immune system such as HIV patients and patients undertaking chemotherapy treatment.
The antifungal drug is sold under the brand names such as Nizoral shampoo from Johnson and Johnson, USA and Sebizole from Douglas Pharmaceuticals, Australia.
The medication is sold in different forms including tablets, topical cream or anti dandruff shampoo.
History The Ketoconazole medication was discovered by lab scientists in the United States in 1976.
However, the drug underwent various clinical tests and further laboratory examinations before it got the approval to be used as medication to be sold commercially.
It was formally released for use and commercial distribution in 1981 with the approval of FDA and the approval followed that of Griseofulvin as being an oral treatment for infections caused by fungi attacks.
Mechanism of Action Ketoconazole works to inhibit the synthesis of fungi that yields the fungi cell membrane and fungi enzymes that lead to fungi growth.
It is used in many other medications and substances such as steroids and in precursors of testosterone due to this synthesis inhibition.
Ketoconazole and Hair Loss Some experiments of the Nizoral shampoo have resulted in s significant treatment of men hair loss.
Experiments conducted in 1998 revealed that a shampoo with a 2% concentration of Ketoconazole could significantly increase the density of hair for the person experiencing hair loss.
However, the experiments were not exhaustive and other experiments have been conducted since then, These experiments reveal that the Nizoral shampoo has a hair growth stimulant that can be used to significantly reverse the effects of hair loss.
Resistance to the Antifungal Not all fungi get inhibited by the Nizoral shampoo or other types of Ketoconazole medication.
Some types of fungi have been observed to be resistant to this medication and will therefore not treat the diseases caused by the fungi.
Especially in cases of HIV, the drug has been noted as being successfully resisted by various yeast infections such as Candida albicans.
This resistance has been explained as being a mutation of the fungi during the synthesis process.
Therefore, if the specific fungi infection does not go away with the treatment, you should seek medical advice and have your doctor get you a replacement drug for your infection.
Side Effects of the Medication The Nizoral shampoo has mild side effects on a few of the patients including dryness of the skin and also oiliness or excessive dryness of the hair and the scalp.
For the other types of mediation, there are possible itchiness and skin rash especially with the cream and other side effects including excessive irritation or sting like effects which commence with the use of the medication.
If you have concerns with the side effects, you should discuss this with your doctor.
You should also alert the doctor in case such side effects arise so as to have them recommend a solution for the side effects.
However, by and large, these side effects are very rare and occur only to about 1% of the users.
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