Vitamin D and Cardiovascular Disease
Vitamin D deficiency is a highly prevalent condition and is independently associated with most CVD risk factors and to CVD morbidity and mortality. Despite a large body of experimental, cross-sectional, and prospective evidence that implicate vitamin D deficiency in the pathogenesis of CVD, the causality of this relationship remains to be established. Most importantly, randomized trials of vitamin D therapy with CVD endpoint are needed to support a role for vitamin D therapy in cardiovascular protection.
Conclusion
Vitamin D deficiency is a highly prevalent condition and is independently associated with most CVD risk factors and to CVD morbidity and mortality. Despite a large body of experimental, cross-sectional, and prospective evidence that implicate vitamin D deficiency in the pathogenesis of CVD, the causality of this relationship remains to be established. Most importantly, randomized trials of vitamin D therapy with CVD endpoint are needed to support a role for vitamin D therapy in cardiovascular protection.
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